laser treatment for senile purpura

The potential for bruising is a frequent concern for patients undergoing minimally invasive procedures, particularly injection-based soft tissue fillers and botulinum toxin type A. Decreasing the risk of this side effect with good technique and careful patient selection is key, but interventions that quicken the resolution of bruising are also helpful. WebStep 1 uses infrared light (800-1,400 nm), high intensity, a smooth adapter, and a constant motion technique. BBL laser therapy is a generally safe and effective treatment that can help address various skin concerns, especially those related to skin appearance, with minimal discomfort. They are formed when blood leaks under the skin or at the joints of blood vessels. Please enable it to take advantage of the complete set of features! doi: 10.1097/PRS.0000000000002184. (2011). Dr. Sips study found that this new intense pulsed light protocol is safe and effective in improving the clinical appearance of senile purpura, as well as preventing future lesions by improving the structure of the skin through increasing skin thickness and strength. ), Wong, HY. It is important to consult a doctor if a child develops any unexplained rash. While no study has assessed the effects of retinol for the treatment of actinic purpura, the combination of topical 0.3% retinol and 1% vitamin K shortened the duration of laser-induced purpura when applied for two weeks prior and two weeks after undergoing treatment with a pulsed dye laser. Senile purpura In S, et al. Dr. Chilukuri reports no relevant financial disclosures. When treating senile purpura, it is important to promote moisture retention of the skin, according to Suneel Chilukuri, MD, the dermatologist at Refresh Dermatology in Houston, Texas. Actinic purpura is fairly common, affecting about 10 percent of people over the age of 50. Patients may appear a little red and feel slightly hot for a couple of hours after treatment, said Dr. Siperstein, And if patients have sun damage, the sun damage becomes darker, then flakes off.. ), Shah, NS, Lazarus, MC, Bugdodel, R. The effects of topical vitamin K on bruising after laser treatment. A thin-partial thickness section of his left forearm was removed and replaced with fenestrated Apligraf. ), (Results showed a significant increase in elasticity and firmness in the treatment group. Three independent blinded observers graded photographs obtained using a purpura scale created by the investigators. The bruise (Figure 1) was divided into quadrants and treated with KTP laser at 14 J/cm2, 9 mm spot, 20 ms, 1064 nm neodymium yttrium aluminum garnet (Nd:YAG) laser at 60 J/cm2, 9 mm spot, 40 ms, intense pulsed light (IPL) with a short-wavelength cut-off filter at 20 J/cm2, 10 x 13 mm spot, program A (LimeLight, Cutera Lasers), versus an untreated control. Three inexpensive, over-the-counter products that are quite effective for senile purpura are CeraVe, Cetaphil, and Aveeno. Both result from blood vessels breaking and leaking. Treatment for Senile Purpura The disorder is considered harmless and fades away with time. This site needs JavaScript to work properly. Specific therapy recommendations, side effects and contraindications will be addressed in this review. injectables) are shallower and are accompanied by less edema than those induced by facial plastic surgery. Two patients experienced minor transient crusting. Hammes S, Kaiser K, Pohl L, Metelmann HR, Enk A, Raulin C. Dermatol Surg. sharing sensitive information, make sure youre on a federal (2002). They are larger than 2 millimeters (mm). One should immediately consult a dermatologist to reduce their appearance. A 590 nm filter with two different fluences is employed. Theyll base the number of treatments on your: Usually, youll need to have three to six BBL treatments spaced a few weeks apart. WebFor patients with extreme cases of bruising, Refresh Dermatology offers laser and light-based therapy that allows for rapid resolution of bruises. Senile Purpura also termed as actinic purpura is a common skin condition that is benign and causes bruises, particularly on forearms and legs. Dont miss out on todays top content on Dermatology Advisor. 2006. pp. Actinic purpura can also be seen on the upper extremities (Figure 1). The primary symptom of actinic purpura is large, purplish red bruises that are most common on the backs of the hands or the forearm. He has been writing for Prime Health Channel more than 750 high quality and informative based medical / health articles for both consumer and professional readers. MeSH Step 1 uses infrared light (8001,400 nm), high intensity, a smooth adapter, and a constant motion technique. Purpura and petechiae can both appear in rash-like clusters. Laser resurfacing as well as chemical peels and microdermabrasion have limited success. The combination therapy not only helps resolve the purpura more quickly, but also prevents some future bruises. Lifshitz OH, et al. They followed the patients 24, 48 hours and seven days after the procedure, and found that accelerated bruise resolution was evident as soon as six hours after laser treatment. Results showed that this treatment has the potential to be an effective antiaging treatment in the future. Combining those 3 advantages make broadband light ideal for senile purpura because it is a condition of decreased skin thickness, increased bruising, and decreased collagen.. 2019 May;32(3):e12861. If there is pain or swelling, the following may help: Unexplained rashes of any kind require medical attention, especially in children. Here's how to recognize anemia rash and what you can do to treat it. However, youll usually need to have multiple treatments to achieve your desired outcome. Dermatol Ther. BBL is a type of laser therapy used to enhance and brighten your complexion by treating skin concerns and stimulating your bodys production of collagen. Epub 2013 May 17. Generally, the larger the affected area, the more severe the underlying bleeding. Br J Dermatol. Therefore the laser energy is more readily absorbed by the target chromophore and these ecchymoses are more amenable to earlier PDL treatment. 17. Epionce uses natural botanical ingredients to most effectively rehydrate and heal skin, Dr. Chilukuri said. As a result, superficial vessels tear and rupture even with negligible trauma. A purpura cluster is not generally irritating or itchy. Berlin JM, et al. Dr. Siperstein was principal investigator of a 10-patient study that compared 5 subjects over the age of 65 with ecchymotic lesions measuring over 1 cm on each forearm to 5 younger subjects under 35 years of age without any ecchymotic lesions. Senile purpura may also be known as Bateman's purpura or actinic purpura. Within 2 weeks of your first treatment, your skin may feel smoother and appear more even and bright. As with the pulse dye laser, patients schedule 1 or 2 sessions of the Nd:YAG laser, spaced about 2 days apart. ), (Double-blind, randomized, placebo controlled study of 22 patients divided into 2 groups; group 1 applied vitamin K cream to half of face and vehicle cream to other half twice daily for 2 weeks before PDL treatment; group 2 applied vitamin K cream to half of face and placebo cream to other half twice daily for 2 weeks after PDL treatment. QJM. For either laser, a treatment session lasts 3 to 4 minutes. Sun damage over a long period of time can also play a role in developing actinic purpura, as this can weaken our connective tissues over time. Gavish is an award-winning freelance medical and health writer and editor with 15 years of experience. One author (KCS) recently treated a five-day-old traumatic ecchymosis of the popliteal fossa with three different types of light to further understand optimal treatment. Step 1. A 590 nm filter with two different fluences is employed. https://www.ncbi.nlm.nih.gov/books/NBK482331/, https://dermnetnz.org/quizzes/different-causes-of-purpura-10-cases/case/10#quiz, New clues to slow aging? Laser hair removal remains a popular nonsurgical procedure. ), Holzer, G, Riegler, E, Honigsmann, H. Effects and side-effects of 2% progesterone cream on the skin of peri- and post menopausal women: results from a double-blind, vehicle-controlled, randomized study. However, lesions on the legs are much harder to treat, as legs take much longer to heal. Senile purpura, also known as Batemans purpura or actinic purpura, is a condition that commonly affects aging skin. ), (Forty total geriatric patients were divided into two groups (those with and without purpura), and were matched for age. Both types of discoloration have associations with underlying health conditions, many of which require medical treatment. Dr. Siperstein started using the Sciton broadband light 5 years ago on patients who were bruising after cosmetic procedures. Senile purpura is characterised by irregularly-shaped macules, 1 4 cm in diameter, that are dark purple with well-defined margins. Actinic purpura is believed to be more common in men. 8600 Rockville Pike 1988. pp. 585-595 nm pulsed dye, pulsed 532 nm and 1064 nm long-pulsed neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers and intense pulsed light may be utilized with best results achieved when treatment is performed 1-2 days after the appearance of purpura. Individuals with chronic sun exposure and/or long-term corticosteriod use (topical and systemic), are also more susceptible to actinic purpura. They are largely common in old people as their skin as well as blood vessels becomes very fragile and thin. WebStep 1 uses infrared light (800-1,400 nm), high intensity, a smooth adapter, and a constant motion technique. However, the discoloration might be permanent even after the lesions fade away causing a brown patch in the affected area. WebSometimes, treatment isnt needed and the purpura goes away on its own. Step 2 employs a 590-nm filter with two different fluences and step 3 utilizes a 560-nm filter. We also sometimes mix retinol with one of these 4 emollients for a greater enhancement of the overall thickness of the upper dermis.. The initial signs of senile purpura are purple or red bruises that have an, Henoch-Schnlein purpura is an inflammation that causes the small blood vessels to leak, leading to a rash. Would you like email updates of new search results? A small 2019 study examined the effects of 5 BBL treatments every 2 weeks and found that BBL is a safe and mildly effective method for reducing enlarged facial pores. Step 3. One treatment session is sufficient for most patients. Results showed that fasting plasma zinc levels were lower in those with senile purpura, than those without. The 3 most common topical options are retinol, arnica, and vitamin K, But studies have been inconclusive for efficacy, she said. Results Topics AZ Dr. Chilukuris laser of choice for purpura is a 595-nm pulse dye laser, with a 6-mm spot Actinic purpura seen on the forearm of an elderly female. In the week following your first treatment, you may notice pigment coming to the surface of your skin. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Purpura are larger than petechiae. Broadband light (BBL) laser therapy, also known as a photofacial, is a generally safe and effective treatment for a variety of cosmetic skin concerns. Beauregard S, Gilchrest BA. Usually, BBL therapy targets your face, neck, chest, arms, and hands though its possible to treat all areas. 2002. pp. The number of ecchymoses on the treated vs untreated arm were significantly reduced (P = 0.02), with an average reduction of 3.5 lesions. Other studies had controls but had contradictory findings.. In most cases, there is no treatment required for actinic purpura. The latest drugs used to treat low platelet count in people with chronic immune (idiopathic) thrombocytopenic purpura (ITP) are romiplostim ( Nplate) and eltrombopag (Promacta). (2020). The spots are also non-blanching, meaning that they do not fade or change color under pressure. WebSenile purpura can be diagnosed based on clinical appearance alone. Please schedule a skin check with one of our board-certified dermatologists at Siperstein Dermatology Group to learn more or have your skin evaluated. An unexplained rash may require treatment, and any child with an unexplained rash and a fever should receive urgent medical attention. After your BBL treatment, you may feel burning, redness, and warmth thats similar to a sunburn. Ostomy Wound Manage. arrow-right-small-blue WebFor patients with extreme cases of bruising, Refresh Dermatology offers laser and light-based therapy that allows for rapid resolution of bruises. You can learn more about how we ensure our content is accurate and current by reading our. BBL treatments increase the thickness of your epidermis (outer layer of skin) and improve collagen and elasticity, which enhances the skins structure. (Geriatric study of prognostic factors of senile purpura (SP) in 1125 elderly Chinese patients. The theory is to thicken the dermis and improve the overall appearance of the skin. (Fluence is increased by 1 J each treatment if no side effects are noted). 2016 Jun;137(6):961e-971e. Fortunately, there are laser and light options that utilize the principle of selective photothermolysis to target hemoglobin within extravasated red blood cells and speed the resolution of purpura. However, people may not like these patches or bruises on their skin so many seek treatment, which may include: Senile purpura does not have any serious complications as it is a benign condition. Lasers and lights: How well do they treat rosacea? Results showed an exponential increase of senile purpura with respect to age and a higher number of males suffering from SP than females.). Protecting your limbs by wearing shin guards can also help prevent minor trauma that causes bruising. Research from 2020 suggests that BBL safely and effectively improves the appearance of senile purpura and prevents new lesions. Petechial rashes can develop in children. Another small 2019 study found that three BBL treatment settings were effective in tightening skin. Once your healthcare provider determines the cause, they can: Change medications causing purpura. Petechiae can develop in small clusters or patches, resembling a rash. National Library of Medicine The epidermal thickness in older untreated skin (red) was on average 15.81% thinner than in younger untreated skin (blue) at baseline: 45.31m vs 53.82 m. vol. BBL treatments help enhance the appearance of skin damaged by factors such as: Dermatologists use BBL laser treatments for conditions such as: It enhances your skins firmness, elasticity, and pigmentation (coloring). The physician performing the procedure will recommend how many BBL treatments youll need. Discuss ways to help you cope with purpura (such as covering up the spots). Senile purpura However, retinoids have many side effects that may outweigh any potential benefits. An unexplained rash may require treatment, and any child with an unexplained rash and a fever should receive urgent medical attention. The fluence of steps 2-3 is increased by 1 J each treatment if no side effects are noted. WebSenile purpura can be diagnosed based on clinical appearance alone. The subsequent extravasation of blood into the surrounding dermis results in the development of dark purple ecchymoses. Specific results include an increase in the expression of the androgen receptor, heat shock protein 37, and procollagen 1 and 3 mRNA in the dermis. 1189-91. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. (2010). All rights reserved. Anything that rehydrates the skin and improves the water barrier will improve the overall health of the skin, he said. Minimal edema but no dyspigmentation was noted. Several studies point to the effectiveness of BBL in improving the appearance of skin. Skin biopsies taken 1 day after the final session were analyzed. Senile purpura is benign and self-resolving. Herbal remedies such as arnica and bromelain- more studies are needed to fully assess the efficacy in reducing the severity of bruising when using these treatments. It was virtually inevitable with the first-generation 585-nm pulsed dye lasers and was typically used as a clinical measure of effective fluence selection. 38. (Double-blind, randomized, placebo controlled study of 22 patients divided into 2 groups; group 1 applied vitamin K cream to half of face and vehicle cream to other half twice daily for 2 weeks before PDL treatment; group 2 applied vitamin K cream to half of face and placebo cream to other half twice daily for 2 weeks after PDL treatment. By Bob Kronemyer; Reviewed by Robyn Siperstein, MD. Purpura refers to purple-colored spots that are most recognizable on the skin. Step 2 employs a 590-nm filter with two different fluences and step 3 utilizes a 560-nm filter. Though the spots are often flat, they can be slightly raised. Although cosmetically displeasing, senile purpura is benign and unrelated to any systemic diseases or blood dyscrasias. and transmitted securely. This is a benign condition of aging and systemic implications and complications have not been reported. Purpura, whether after trauma or an aesthetic procedure, is undesirable to patients. Results are promising in using these treatments, however more studies are needed to fully examine the safety and benefits of these therapies. It may be helpful to arrange a payment plan ahead of time. Step 2 employs a 590-nm filter with two different fluences and step 3 utilizes a 560-nm filter. Purpura form when tiny blood vessels called capillaries burst and leak, causing blood to pool beneath the skin. All three techniques showed improvements in zygomatic (cheekbone) wrinkles, nasolabial folds, and marionette lines. Histologically, the epidermis is thinned, and the dermis demonstrates significantly reduced amounts of collagen replaced by abnormal elastic fibres, as well as extravasated red blood cells. You can expect to see visible changes to your skin within a few days or weeks of your first BBL treatment. Broadband light treatment using static operation and constant motion techniques for skin tightening in Asian patients. The aging skin. Purpura (or bruising) is often noted in patients after pulsed-dye laser treatment. Your doctor can prescribe topical retinoids that thicken your skin to prevent further skin aging. 2000. pp. Semin Cutan Med Surg. He healed well post-peratively and did not experience new tears,brusing or trauma to the grafted location after 15 months. Patients should be educated on sun protection measures, including sunscreen application and sun-protective clothing to protect their skin from further photodamage. The most recent report on lasers for bruise reduction comes from a group at Baylor University (Mayo TT, Khan F, Hunt C, et al. Step 2. 2013 Sep;69(3):438-43. doi: 10.1016/j.jaad.2013.04.015. Varying in size, large purpura spots are called ecchymosis while the smaller ones are termed as petechiae. 2023 Healthline Media LLC. Purpura is often frustrating and often cosmetically bothersome, but luckily it is usually not worrisome to your health. vol. Histopathology consists of features of aging skin including flattening of the dermal-epidermal junction, decreased elastic fibers, fibroblasts and collagen, as well as thinning of dermal vasculature. (2019). Broadband light (BBL) laser therapy, also known as a photofacial, is a generally safe and effective treatment for a variety of cosmetic skin concerns. A 590 nm filter with two different fluences is employed. A split-face randomized controlled trial of treatment with broadband light for enlarged facial pores. WebMany practitioners have employed the theory of selective photothermolysis, using laser and light devices, to target hemoglobin and its breakdown products to speed time to bruise resolution. The latest drugs used to treat low platelet count in people with chronic immune (idiopathic) thrombocytopenic purpura (ITP) are romiplostim ( Nplate) and eltrombopag (Promacta). Step 1. Modulating diseased skin with tissue engineering: actinic purpura treated with apligraf. Lasers may also be used to treat lesions and help them fade away faster. An unexplained rash may require treatment, and any child with an unexplained rash and a fever should receive urgent medical attention. Fair skinned older people are more likely to develop the condition. 2005. pp. (2019). McKnight B, et al. However, at Refresh Dermatology, Epionce is the favored moisturizer. The square area of ecchymoses on the treated vs untreated arm were also significantly reduced (P = 0.04), with an average reduction of 12.7 cm. Senile purpura, also known as Batemans purpura or actinic purpura, is a condition that commonly affects aging skin. Some patients undergo a follow-up laser treatment 2 days later, with the exact same settings, followed immediately by combined radiofrequency (RF) and ultrasound (Exilis Ultra). Broadband light (BBL) laser therapy, also known as a photofacial, is a generally safe and effective treatment for a variety of cosmetic skin concerns. At postoperative day (POD) five or six, the bruise was divided and part was treated with a PDL (V-beam, Candela) at 6 J/cm2, 10 mm spot, 10 ms pulse duration, and cryogen 30 milliseconds with a 20 millisecond delay for three passes. They found that the ecchymosis continued to worsen over the next two to three days, so they defined POD five as the time of initial treatment for this study. The most common factor that most directly affects the development of actinic purpura is thin, easily damaged skin. With this protocol, patients will typically notice less bruising within about 8 to 12 weeks, Dr. Chilukuri said. Seeking emergency care is crucial if a child has an unexplained rash and a fever. For at least 1 week before BBL, avoid waxing, chemical peels, and products containing retinol, salicylic acid, or glycolic acid. 2009;10(3):153-68. doi: 10.2165/00128071-200910030-00002. The protocol consisted of 4 weekly sessions of broadband light treatment. Youve viewed {{metering-count}} of {{metering-total}} articles this month. However, people may not like these patches or bruises on their skin so many seek treatment, which may include: Supplementation with vitamin C Intake of flavonoids and antioxidants Retinoid for further prevention Please schedule a skin check with one of our board-certified dermatologists at Siperstein Dermatology Group to learn more or have your skin evaluated. See additional information. He healed well post-peratively and did not experience new tears,brusing or trauma to the grafted location after 15 months. Optimal Therapeutic Approach for this Disease, Unusual Clinical Scenarios to Consider in Patient Management. The following day both sides improved from the treatment but the higher fluence setting was more impressive (Figure 5). Many practitioners have employed the theory of selective photothermolysis, using laser and light devices, to target hemoglobin and its breakdown products to speed time to bruise resolution. The fluence of steps 2-3 is increased by 1 J each treatment if no side effects are noted. MEDICAL THERAPIES (the goal is to prevent further skin aging). Purpura may be petechiae that have spread and joined together, forming larger areas of discoloration. - Evidence-Based Guidance A thin-partial thickness section of his left forearm was removed and replaced with fenestrated Apligraf. Purpura and petechiae can both appear in rash-like clusters. We avoid using tertiary references. Lasers may also be used to treat lesions and help them fade away faster. According to estimates, 2.5% of children taken to the emergency room experience them as a symptom. For at least 48 hours following BBL treatment, avoid anything that causes sweating or flushing. The doctor studies all symptoms and medical history of the patient and also undergoes a physical test. vol. The site is secure. Alam M, Voravutinon N, Warycha M, Whiting D, Nodzenski M, Yoo S, West DP, Veledar E, Poon E. J Am Acad Dermatol. One 2015 study also found that applying an epidermal growth factor directly to the skin twice per day thickened the skin and decreased the number of purpuric lesions the people in the study experienced. Step 2 employs a 590-nm filter with two different fluences and step 3 utilizes a 560-nm filter. Henoch-Schnlein purpura: What you need to know, Why do bruises itch? Despite their widespread use, however, there is a paucity of published literature on the topic. The vessel walls of the dermis are normal in structure. Step 2 employs a 590-nm filter with two different fluences and step 3 utilizes a 560-nm filter. vol. For this reason they believe earlier violaceous to erythematous bruises respond better to PDL. Senile purpura, also known as Batemans purpura or actinic purpura, is a condition that commonly affects aging skin. Two blinded evaluators graded the bruises at 30 minutes, three days and seven days. However, the risk of retinoid dermatitis may outweigh the benefits. Diabetes, rheumatoid arthritis, and lupus may also increase the likelihood of developing the lesions. Next, we explore their causes and treatments, and when to contact a doctor. Senile purpura although harmless, if left untreated may be recurring in occurrence. Senile purpura 18. This may spread over a larger area of skin or be confined to a single area. Fair skinned older people are more likely to develop the condition. Dr. Chilukuris laser of choice for purpura is a 595-nm pulse dye laser, with a 6-mm spot With 1 or 2 treatments, the bruise is gone within anywhere from 24 hours to 96 hours, Dr. Chilukuri said. Both petechiae and purpura clusters tend to have rash-like appearances. 2010. pp. Thanks for visiting Dermatology Advisor. Purpura is a transient phenomenon that usually lasts 7-14 days. A randomized, placebo-controlled, double-blind study to evaluate the efficacy of a citrus bioflavanoid blend in the treatment of senile purpura. Although laser hair removal is generally safe, side effects are possible. Procedures such as hyaluronic acid or calcium hydroxyapatite injections into the dorsal hands to camouflage purpura have been tried; bruising secondary to the injections may negate the potential benefits. Learn about the potential side effects, the mythical cancer connection, and, From lightening creams and OTC peels to laser therapy, there are many different treatments for hyperpigmentation. Lasers may also be used to treat lesions and help them fade away faster. With age and photodamage, the dermal tissues become thin and increase the fragility of blood vessels. Learn all about the causes, symptoms, and treatments for purpura here. Step 1. Actinic purpura is caused by skin aging, both intrinsic and solar, and can occur with or without skin trauma. We also discuss how it's different from other types of hemophilia and how to. They can also develop under the mucous membranes, such as those in the mouth or nose. Targeting senile purpura with broadband light, Outside-the-Box: Tips for treating eczema and more, Avoiding Complications and Risk With Nonsurgical Cosmetic Procedures, Adding IV Therapy to the Dermatology Practice. Last medically reviewed on July 16, 2021. Avoid direct sunlight or tanning beds for 4 to 6 weeks before and after each session. At that time all quadrants were treated with the KTP laser at the same settings, and only one hour later there was dramatic resolution of the treated areas (Figure 3). If they see that your ecchymoses or lesions are painless and restricted to the hands and forearms with no other abnormal bleeding, theyll likely diagnose you with actinic purpura. You may experience sensations, pulses, and mild pain. Kaufman and Green have performed research and served on the speakers bureau for Cutera Lasers. [24] Alpha hydroxy acids. Fortunately, there are laser and light options that utilize the principle of selective photothermolysis to target hemoglobin within extravasated red blood cells and speed the resolution of purpura. BBL treatments usually last around 30 minutes, depending on the size of the treatment area. Last medically reviewed on January 19, 2021. Yu W, et al. Plast Reconstr Surg. In most cases, there is no treatment required for actinic purpura. Some common treatments for It may also boost your bodys self-healing ability to regrow healthy skin. Some common treatments for Infrared Light (800-1,400 nm) is used with high intensity, a smooth adapter and a constant motion technique. However, people may not like these patches or bruises on their skin so many seek treatment, which may include: Supplementation with vitamin C Intake of flavonoids and antioxidants Retinoid for further prevention Federal government websites often end in .gov or .mil. Dr. Sips study found that this new intense pulsed light protocol is safe and effective in improving the clinical appearance of senile purpura, as well as preventing future lesions by improving the structure of the skin through increasing skin thickness and strength. Too high of an energy setting will cause the skin to blister. Your doctor will ask about your symptoms and medical history and do a physical assessment. Step 3. It was virtually inevitable with the first-generation 585-nm pulsed dye lasers and was typically used as a clinical measure of effective fluence selection.

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laser treatment for senile purpura

laser treatment for senile purpura

laser treatment for senile purpura

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