The plant has various other common names including: Back in the day, the Justicia flower was boiled and used to solve anemia problems. Acute toxicity was determined in two phases using Lorke method. View abstract. Article By using this website, you agree to our California Privacy Statement, Ashwagandha tea: 10 benefits, side effects and recipes, 7 interesting health facts about Black sapote fruits. 2003;66:1499503. We use cookies on this website, you can read about them here. The flowers are slightly fragrant and mostly sterile. Clinical Guide to Laboratory tests. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). Results obtained from the acute oral toxicity study revealed tolerance of experimental rat to acute administration of J. carnea ethanol extracts since no mortality and signs of toxicity were observed after 24h (Table1). This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). Turn off the heat and then soak the leaves into the pot. Article The mixture was allowed to cool and centrifuged at 650g for 10min to obtain the supernatant. One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. Data were analyzed using one-way analysis of variance (ANOVA) using Statistical Product and Service Solutions (SPSS) version 17.0 and results were expressed as meanSEM. The animals were initially examined for any signs of toxicity after 60min of administration and further observed for a period of 24h. The absence of rat mortality in phase I necessitated the conduct of the second phase. Another plant with this benefit is fertility tree. When it comes to blood boosting and treatment of anemia, justicia carnea has proven beyond doubt to be an effective remedy. 1978;52:30210. Microsomal lipid peroxidation. Rather it can assist with improveing liver function such as detoxification. The mixture was incubated at 28C for 30min and the absorbance read at 550nm against the reagent blank. This is in agreement with previous work on the reversed effect of J. carnea leaf extract on anaemia induced experimental rat [9, 21]. Ewe eje is good for the liver. Anti-obesity, antioxidant and in silico evaluation of Justicia carnea https://doi.org/10.1016/j.jep.2007.02.011. 2003;84:99104. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. View abstract. Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. Luckily, the unique flowers of Jacobinia carnea and its foliage are free from major pest and disease concerns. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. View abstract. Aim. long (20 cm), densely packed with pink to crimson tubular flowers. Anthonia OC, Ikechukwu UR, Uzoma NO, Sunday ELU. Total reaction mixture of 3ml contained 2.95ml of 0.05M sodium carbonate buffer (pH10.2), 0.02ml tissue sample and 0.03ml of epinephrine (2mM) in 0.005N HCl was used to initiate the reaction. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. Badami S, Aneesh R, Sankar S, Sathishkumar MN, Suresh B, Rajan S. Antifertility activity of Derris brevipes variety coriacea. Tags: benefits of justicia carnea, health benefit of justicia carnea, justicia carnea . This could possibly indicate SOD stimulating effects of J. carnea leaf ethanol extract. Wash the Justicia carnea leaves thoroughly to eliminate all forms of insects and dust. It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. Some vitamin composition of Justicia carnea leaves This suggested that the extract did not alter tissue function in converting harmful hydrogen peroxide to water and oxygen. Another health benefit of ewe eje leaves is in cardiac protection and hypolipidemic effect. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. Studies have also confirmed this claim. Mr. E.S. Antioxidants & redox signaling Forum Review. Different researches performed on wistar rats has proven the non toxicity of justicia carnea. Note: A=change in absorbance, TV=total volume, SV=sample volume, =molar extinction=4020M1cm1, TP=total protein. 2. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. The plume flowers grow atop a crown of foliage in large dense clusters. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. Anal Biochem. Omogunwa is a graduate of Biochemistry from the Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. I also conduct research on molecular basis of human diseases, linking the pharmacological properties of certain natural products and their mechanisms of actions to the treatment of such diseases. This is . SOD is involved in the dismutation of the highly reactive superoxide anion to molecular oxygen (O2) and to less reactive hydrogen peroxides (H2O2) species, whereas CAT removes hydrogen peroxide (H2O2) and toxic hydroxyl radical into water molecule [35]. Ewe eje is a rich source of phytochemicals, minerals and vitamins. Becoming a contributing member of Gardenia is easy and can be done in just a few minutes. 1. Antianaemic potentials of some plant extracts on phenyl hydrazineinduced anemia in rabbits. Justicia Carnea Leaf Benefits - Ewe eje - besthomediet The protein content may help in cellular functions and are building blocks for structural and functional biomolecules. The significant decrease in kidney GSH at 1200mg/kg could be due to ample dietary bioactive constituents in the extract that requires frequent conjugation of GSH in the cell or oxidation to oxidized glutathione (GSSG). The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. The reference cuvette contained 2.95ml buffer, 0.03ml of substrate (epinephrine) and 0.02ml of water. Macrocytic and hypochromic anemia usually results due to increased mean corpuscular volume (MCV) and decrease in mean corpuscular hemoglobin concentration [30]. We'll respect your privacy and unsubscribe at any time. de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. Justicia carnea needs bright, indirect light to thrive. The plant looks great along garden borders and near building foundations. Yes my readers. Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Based on estimation by World Health Organization (WHO), larger percentage (between 80 and 90%) of the worlds population especially in developing countries depends on traditional system of medicine [1, 2]. Nunes TRS, Cordeiro MF, Beserra FG, et al. Safety assessment of Uvaria chamae root extract: acute and subchronic toxicity studies. Terms and Conditions, Significant (P<0.05) decrease observed in liver total protein of rat administered with 1200mg/kg of extract could be due to intrinsic factors in-vivo that might not necessarily indicate adverse reaction of the extracts. Ethnomedical study and iron content of some medicinal herbs used in traditional medicine in cote divoire for the treatment of anaemia. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). This post was last modified on January 2, 2023 5:23 pm. Acute and chronic toxicity of the aqueous extract of Artemisia afra in rodents. Only plants will be removed from the collection. The catalase activity was calculated using the expression: Note: A=change in absorbance, TV=total volume, TP=total protein, SV=sample volume, =molar extinction=40M1 cm1. This is not a big concern as it wont kill the plant and you will find a solution at your local gardening center. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. Braz. Haematological and biochemical studies on Justicia carnea - PubMed Google Scholar. Oyenihi OR, Brooks NL, Oguntibeju OO. The weight of organs (liver and kidney) reduced steadily in a concentration dependent manner. In this article i will take you through the nutritional and medicinal benefits of justicia carnea. Studies on The Phytochemical and Nutritional Composition of Aqueous 7 Potential Health Benefits Of Justicia Carnea (Ewe Eje) 16. Ewe eje isnt capable of causing any side or negative effects if consumed moderately. There are several nutritional benefits of justicia carnea leaves. How often should it be watered? degree in Biochemistry fromUniversity of Ado-Ekiti, Ekiti State, Nigeria and University of Ibadan, Nigeriarespectively. Ani, Onuabuchi & Udedi, Stanley & Asogwa, Kingsley & Enemali, Michael & Onwelumadu, Chigozie & Ikedife, Kenneth. Histopathological examinations of sections of the liver collected from the 4 Group 2, 3, 4, 5, 6 were respectively administered orally with 50, 100, 500, 800 and 1200mg/kg body weight of JCEE once daily for 14days using an oral gavage. 2019;30(4):64554. Corroborating with the results of the antioxidant system and weight of the liver, continuous exposure to higher dose (1200mg/kg) of JCEE could result in hepatic damage. Prevent this by spraying the leaves with water. International Journal of Biochemistry Research & Review. Justicia pectoralis might have many different effects in the body. The effect of the ethanol extract of Justicea. Beijing: Chemical Press; 2011. Fertility leaves: Benefits and side effects, Guava Leaf Tea: Health Benefits of Guava Leaves, Coriander seeds: 18 benefits Coriandrum sativum fruits and seeds, Rapini: Nutritional facts, benefits, side effects and care. 400). Authors KOK and ESA performed the statistical analysis and managed the analyses of study. Hence, Justicia carnea can be used to strengthen the immune system. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. 34-45. Watering depends on humidity and temperature. It has already been pointed out that this plant is used traditionally to boost blood production among the people of southern Nigeria. This information may not fit your specific health circumstances. Sci. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. The shrubby habit of the plant is well-suited for both containers and outside planting. Article Another strong benefits of justicia carnea leaves is in lipid profile. J Ethnopharmacol. Also observed is a distortion in the walls of the blood vessels (red arrow), pyknotic hepatocytes and signs of inflammation (red arrow), Photomicrographs of kidney sections stained with Haematoxylin and Eosin (Mag. Onyeabo, Chimaraoke & Achi, Ngozi & Chima, Ekeleme-Egedigwe & Ebere, Chidinma & Okoro, Chidinma. Safety assessment of oral administration of ethanol extract of Justicia This research focused on the safety and in vivo antioxidant status of healthy albino rats exposed to J. carnea leaf ethanol extract. [1] The perennial plant is native to the Atlantic Forest ecoregions of eastern Brazil . It does not tolerate low temperatures at all. It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America.The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. statement and PDF Effects of Ethanol Leaf Extract of Justicia Carnea on Biochemical Not sure which Justicia to pick?Compare All Justicia. Join now and start creating your dream garden! The Pharmacobiochemical Effects of Ethanol Extract of Justicia secunda Safety assessment of oral administration of ethanol extract of, $$ \mathrm{Total}\ \mathrm{protein}\kern0.5em =\kern0.5em \frac{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{sample}}{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{standard}}\kern0.5em \times \kern0.5em \mathrm{Concentration}\ \mathrm{of}\ \mathrm{standard} $$, $$ \mathrm{Catalase}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}\right)=\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{SOD}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}/\mathrm{mg}\ \mathrm{protein}\right)\kern0.5em =\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{Concentration}\kern0.5em \mathrm{of}\kern0.5em \mathrm{reduced}\kern0.5em \mathrm{GSH}\kern0.5em =\kern0.5em \frac{\left(\Delta \mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\left(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}\right)} $$, $$ \mathrm{Malondialdehyde}\kern0.5em =\kern0.5em \frac{\left(\mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\Big(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, https://doi.org/10.1186/s40816-020-00234-4, https://doi.org/10.1016/j.jep.2015.06.005, https://doi.org/10.1016/j.joad.2015.08.006, https://doi.org/10.1016/j.jep.2005.06.013, https://doi.org/10.3109/08860220903367585, https://doi.org/10.1590/S0102-695X2011005000196, https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867, https://doi.org/10.35841/biomedicalresearch.30-18-666, https://doi.org/10.1016/j.jep.2007.02.011, https://doi.org/10.1186/s40816-019-0104-4, https://doi.org/10.1016/j.fitote.2008.02.005, https://doi.org/10.1016/j.jada.2008.06.430, https://doi.org/10.1016/j.biocel.2006.07.001, https://doi.org/10.1186/s12906-015-0760-y, http://creativecommons.org/licenses/by/4.0/. Justicia carnea belongs to the family- Acanthaceae. J Ethnopharmacol 2000;70(2):151-159. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. They are also needed in strong bone formation, and in cellular and neuronal functions. Google Scholar. Article ID 687197, 2013; p. 13. https://doi.org/10.1155/2013/687197. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. PDF Biomedical Research 2019; 30 (4): 645-654 ISSN 0970-938X - Allied Academies It helps in replenishing blood lost during period. The cuttings should be placed in individuals pots and put under glass or shaded location, away from direct sunlight. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. Cover and leave for about fifteen minutes. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. . The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. Recently, it has also been reported that the species possess cardioprotective properties, antioxidant and are generally rich in vitamins and minerals [10,11,12]. Superoxide dismutase (SOD) activities were elevated across all doses in the liver with significant (p<0.05) difference only observed in the highest dose (1200mg/kg) while kidney showed no significant difference compared to the control. Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. Studies have shown that ewe eje isnt capable of causing damage to the liver. During the growing season, the justicia (plant) should be watered thoroughly with room temperature water. 2004;19(12):16. Pinch Justicia carnea plants back after theyve flowered. Aim. Except the group that received 1200mg/kg JCEE which showed significant (p<0.05) elevation of SOD and MDA in the liver, other doses (<1200mg/kg) demonstrated no significant difference compared to the control. PDF Evaluation of Anti-inflammatory and Analgesic Properties of Justicia While graded doses of J. carnea ethanol extract showed no significant difference in the liver and kidney GSH compared to the control, only rats that received 1200mg/kg body weight JCEE statistically decreased in the kidney. Bottom Line. Caterpillars may be an occasional problem, chewing down on some of the foliage. In this study, nutritive potentials and effects of aqueous extract of Justicia carnea leaves on biochemical indices of anaemic male Wistar albino rats were investigated. The plants cannot be propagated with seeds. Prof. F.O. It has been shown also that other specie of justicia improve central nervous system functions and health and protect it from toxic damages. W Afr J Biol Sci. Cite this article. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). Names of Justicia Betonica in various languages of the world are also given. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. Toxicity studies of medicinal plants used in sub-Saharan Africa. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. The possible anti-anaemic property of the leaf could be linked to the improved hemoglobin, PCV and RBC observed in this study. How long does it take for Aju mbaise to work. Evid Based Complement Alternat Med. Extinction coefficient () of MDA TBA complex=1.56105M1cm1. The Pros and Cons of Creatine You Should Know.

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